Dr. Dale Bredesen is internationally recognized as an expert in the mechanisms of neurodegenerative diseases such as Alzheimer’s disease.
He earned his medical degree from Duke University Medical Center and served as Chief Resident in Neurology at the University of California, San Francisco (UCSF), before joining Nobel laureate Stanley Prusiner’s laboratory at UCSF as an NIH postdoctoral fellow. He has held faculty positions at UCSF; UCLA and the University of California. Dr. Bredesen also directed the Program on Aging at the Burnham Institute before coming to the Buck Institute in 1998 as its founding president and CEO. In 2013, he returned to UCLA as the Director of the Easton Center for Alzheimer’s Disease Research.
Dr. Bredesen’s research explores previously uncharted territory in explaining the physical mechanism behind the erosion of memory seen in Alzheimer’s disease, and has opened the door to new approaches to treatment. This work has led to the identification of several new therapeutic processes that are showing remarkable early results.
He introduced the notion of dependence receptor while he was working on the low affinity receptor p75ntr and have shown the importance of this notion in neurodegenerative diseases